Professor in Preventive Medicine and Public Health, Universidad de Oviedo.
ORCID ID: 0000 0001 5150 1209
Adonina Tardón has a PhD in Medicine and Surgery; she is a specialist in Preventive Medicine and Public Health, a member of the Cuerpo Médico de Sanidad Nacional (National Health Medical Corps) and a Professor in Preventive Medicine and Public Health at the Universidad de Oviedo.
She has extensive university teaching experience at undergraduate and postgraduate level. She has led the teaching programme on Preventive Medicine and Public Health at the Universidad de Oviedo since 1 September 2016. She has supervised 24 research dissertations and Diplomas of Advanced Studies on the Cancer Research (15) and Diagnosis in Community Health (9) programmes. She has supervised nine dissertations on the Master’s degrees in Biomedicine and Molecular Oncology; Occupational Risk Prevention, and Emergency and Disaster Analysis and Management.
Over the last five years, she has supervised eight PhD theses on the Diagnosis in Community Health and Cancer Research programmes. Two of these theses received the Universidad de Oviedo outstanding PhD award and one received international honours.
She was Scientific Secretary of the Instituto Universitario de Oncología del Principado de Asturias (IUOPA) in the Universidad de Oviedo from January 2000 to September 2016, and has led IUOPA’s Environmental and Molecular Epidemiology research group since January 2000.
Since January 2007, she has been head of research group 53 in CIBERESP (Network Centre for Biomedical Research: Epidemiology and Public Health), where she has been administrative coordinator of programme five and a member of the CIBERESP Management Committee since January 2011.
Finally, in July 2017, she was selected to join ISPA as principal investigator of this consolidated research group.
She is author of 266 scientific articles in journals with international-level impact, her H-index is 41 and she has a total of 5,785 citations: 1400 in bladder cancer, 300 in lung cancer and 1254 in the field of childhood and environment. She has received funding for three six-year research periods, and has secured 20 funded research projects from national and international agencies. Additionally, she has secured and completed ten private-sector contracts for consultancy and the production of epidemiological reports and assessments. In January 2017, she entered into a partnership with the Consejería de Sanidad del Principado de Asturias to carry out knowledge transfer activities related to the COHORTE INMA Asturias (Asturian Child and Environment Cohort) study of the Universidad de Oviedo .
Member of the Comité de Ética de la Investigación del Principado de Asturias) (Research Ethics Committee of Asturias). Appointment through Consejería de Sanidad Resolution of 23 April 2014; the post is ongoing.
Member of the Comité de Ética de la Universidad de Oviedo (University of Oviedo Ethics Committee). Appointment on 13 April 2018; the post is ongoing.
Member of the Ponencia Técnica de Cáncer Laboral (Technical Platform on Occupational Cancer). Comité de Cáncer del Principado de Asturias (Cancer Committee of Asturias). Appointment on 25 March 2015; the post is ongoing.
|Arcos González, Pedro Ignacio||Universidad de Oviedo||Research/Teaching||R3|
|Castro Delgado, Rafael Vicente||Universidad de Oviedo||Research/Clinical/Teaching||R3|
|Fernández Iglesias, Rocío||CIBER||Research/Teaching||R1|
|Fernández Somoano, Ana||Universidad de Oviedo||Research/Teaching||R3|
|Fernández Tardón, Guillermo||Universidad de Oviedo||Research/Teaching||R1|
|Riaño Galán, Isolina||SESPA/Universidad de Oviedo||Research/Clinical/Teaching||R2|
|Rivas del Fresno, Manuel||SESPA||Research/Clinical||R2|
|Rodríguez Dehli, Ana Cristina||SESPA||Research/Clinical||R2|
|Tardón García, Adonina||Universidad de Oviedo||Research/Teaching||R4|
|Arias Díaz, María Cristina||Universidad de Oviedo||Research||No classification|
|Arias Fernández, María Asunción||Fundación de Investigación Oftalmológica (FIO)||Research||No classification|
The Molecular and Environmental Epidemiology research group is part of the Instituto Universitario de Oncología (IUOPA) in the Universidad de Oviedo, and operates within the Preventive Medicine and Public Health section of the Faculty of Medicine and Health Sciences.
It has a history of over 20 years of collaborative work. Since 1997, the group’s scientific work has focused on the following fields: occupational and molecular epidemiology and the genetic epidemiology of cancer – particularly lung and bladder cancer – (CAPUA Study, Spanish Bladder Cancer, MCC Spain); environmental epidemiology (COHORTE INMA Asturias); mortality in small areas of Spain (MEDEA Group); emergencies, disasters, climate change, emergent diseases and epidemiological analysis of environmental epidemiology.
We are the research group for Asturias in the Spanish Bladder Cancer study, conducted in partnership with the NIH’s National Cancer Institute in the US. This epidemiological study of bladder cancer is the most extensive and productive of its kind in Spain, having generated over 65 articles on a range of issues related to the development of bladder cancer in several journals of international prestige.
The group was responsible for designing and setting up the Universidad de Oviedo’s CAPUA (Lung Cancer in Asturias) Study which has received funding from national and international agencies and has resulted in the publication of 42 scientific articles, 75% of which appeared in first-quartile journals. It forms part of the INTERNATIONAL LUNG CANCER CONSORTIUM, http://ilcco.iarc.fr/ and the IARC’s SYNERGY PROJECThttp://synergy.iarc.fr.
The research group represents Asturias in the the CIBERESP MCC-SPAIN multi-case-control study, http://www.mccspain.org which was designed in Spain to investigate the influence of environmental factors and how they interact with genetic factors in colorectal, breast, gastroesophageal and prostate cancer tumours. The study has produced 36 scientific articles to date, most in first-quartile journals.
The group is responsible for the Cohorte INMA Asturias (Asturian Child and Environment Cohort) study, in which a cohort of 12-week-old babies was established from the population of Asturian Health District III in 2004. To date, the cohort has been monitored up to 8 years of age, with a response rate of 92.41%. We are currently in the phase of monitoring up to 11 years of age . Research on the INMA Asturias cohort focuses on obesity and its repercussions in childhood, taking into account all exposures to risk since pregnancy. We have also been studying the presence and concentration of persistent toxic substances in the pregnant women and their children.
The research group is also responsible for the Universidad de Oviedo’s Emergency and Disaster Research Unit http://www.uniovi.net/uied, whose research is focused on public health during emergencies and disasters. We have developed the Advanced Off-site Triage Model , which is used by a number of the Spanish emergency services. We have conducted studies on how industrial activity impacts the population, climate change and disasters, as well as the epidemiology of disasters in a general sense. One of our current lines of research explores the impact of pollution by analysing emergency calls to an emergency control centre.
The group leads the Air Quality and Health Study, which was set up in partnership with the Dirección General de Salud Pública (General Office of Public Health) in 2016, in order to develop an Epidemiological Surveillance System for diseases related to air pollution in Asturias. We monitored indicators for health and air quality between 2003 and 2015 to explore the relationship between them, and thereby understand the negative effects of pollution on the health of the population. We have been continuing to study the time series from 2016 onwards, and aim to identify geographical patterns in the rates of emergency hospital admissions for heart attacks, angina, asthma and chronic obstructive pulmonary disease in the health districts of Oviedo, Gijón and Avilés.
We are the research group participating in the MEDEA Study for Asturias. The Mortality in Small Areas of Spain and Socio-Economic and Environmental Inequalities (MEDEA) project is a national, multi-centre study which aims to describe the geographic patterns in mortality in a range of different Spanish cities and relate these patterns to the socioeconomic and environmental characteristics of small areas (the project’s unit of analysis is the ‘sección censal’, or census tract). Since 2017, we have been leading the MEDEA3 project (the third phase of the project). In the current project phase, the aim is to study the aforementioned patterns and the causes of death in the main cities of Asturias, exploring certain issues that were not addressed earlier in the project, and continuing the task of monitoring mortality initiated in previous phases.
- AUTHORS: Riaño-Galán I, Fernández-Somoano A, Rodríguez-Dehli C, Valvi D, Vrijheid M, Tardón A.
TITLE: Proatherogenic Lipid Profile in Early Childhood: Association with Weight Status at 4 Years and Parental Obesity.
J Pediatr. 2017 Aug; 187:153-157.e2. doi: 10.1016/j.jpeds.2017.04.042. Epub 2017 May 18. PubMed PMID: 28529017
- AUTHORS: Costa O, Lopez-Espinosa MJ, Vizcaino E, Murcia M, Iñiguez C, Navarrete-Muñoz EM, Grimalt JO, Tardon A, Ballester F, Fernandez-Somoano A.
TITLE: Dietary and Household Sources of Prenatal Exposure to Polybrominated Diphenyl Ethers (PBDEs) in the INMA Birth Cohort (Spain).
Environ Sci Technol. 2016 Jun 7;50(11):5935-44. doi: 10.1021/acs.est.5b06263. Epub 2016 May 13. PubMed PMID: 27123793.
- AUTHORS: Rodríguez-Dehli AC, Riaño-Galán I, Fernández-Somoano A, Navarrete-Muñoz EM, M, Vioque J, Tardón A.
TITLE: Hypovitaminosis D and associated factors in 4-year old children in northern Spain.
An Pediatr (Barc). 2017 Apr;86(4):188-196. doi: 10.1016/j.anpedi.2016.02.003. Epub 2016 Mar 14. Spanish. PubMed PMID: 26988234.
- AUTHORS: Lopez-Espinosa MJ, Costa O, Vizcaino E, Murcia M, Fernandez-Somoano A, Iñiguez C, Llop S, Grimalt JO, Ballester F, Tardon A.
TITLE: Prenatal Exposure to Polybrominated Flame Retardants and Fetal Growth in the INMA Cohort (Spain).
Environ Sci Technol. 2015 Aug 18;49(16):10108-16. doi: 10.1021/acs.est.5b01793. Epub 2015 Aug 4. PubMed PMID: 26181825; PubMed Central PMCID: PMC4573079.
- AUTHORS: Fernández-Somoano A, Llop S, Aguilera I, Tamayo-Uria I, Martínez MD, Foraster M, Ballester F, Tardón A.
TITLE: Annoyance Caused by Noise and Air Pollution during Pregnancy: Associated Factors and Correlation with Outdoor NO2 and Benzene Estimations.
Int J Environ Res Public Health. 2015 Jun 18;12(6):7044-58. doi: 10.3390/ijerph120607044. PubMed PMID: 26095869; PubMed Central PMCID: PMC4483747.
- AUTHORS: Rodríguez-Dehli AC, Riaño Galán I, Fernández-Somoano A, Navarrete-Muñoz EM, Espada M, Vioque J, Tardón A.
TITLE: Prevalence of vitamin d deficiency and insuffiency and associated factors in pregnant women of northern Spain.
Nutr Hosp. 2015 Apr 1;31(4):1633-40. doi: 10.3305/nh.2015.31.4.8448. Spanish. PubMed PMID: 25795951.
- AUTHORS: Vizcaino E, Grimalt JO, Glomstad B, Fernández-Somoano A, Tardón A.
TITLE: Gestational weight gain and exposure of newborns to persistent organic pollutants.
Environ Health Perspect. 2014 Aug; 122(8):873-9. doi: 10.1289/ehp.1306758. Epub 2014 May 2. PubMed PMID: 24786842; PubMed Central PMCID: PMC4123021.
- AUTHORS: Vizcaino E, Grimalt JO, Fernández-Somoano A, Tardon A.
TITLE: Transport of persistent organic pollutants across the human placenta.
Environ Int. 2014 Apr; 65:107-15. doi: 10.1016/j.envint.2014.01.004. Epub 2014 Jan 28. PubMed PMID: 24486968.
- AUTHORS: Fernández-Somoano A, Tardon A.
TITLE: Socioeconomic status and exposure to outdoor NO2 and benzene in the Asturias INMA birth cohort, Spain.
J Epidemiol Community Health. 2014 Jan;68(1):29-36. doi: 10.1136/jech-2013-202722. Epub 2013 Sep 2. PubMed PMID: 23999377; PubMed Central PMCID: PMC3888634.
- AUTHORS: Fernández-Somoano A, Hoek G, Tardon A.
TITLE: Relationship between area-level socioeconomic characteristics and outdoor NO2 concentrations in rural and urban areas of northern Spain.
BMC Public Health. 2013 Jan 25; 13:71. doi: 10.1186/1471-2458-13-71. PubMed PMID: 23351567; PubMed Central PMCID: PMC3659019.
- AUTHORS: Miguel García-Villarino, Isolina Riaño-Galán, Ana Cristina Rodriguez-Dehli, Esther Vizcaino, Joan O. Grimalt, Adonina Tardón, Ana Fernández-Somoano.
TITLE: Prenatal exposure to persistent organic pollutants and anogenital distance in children at 18 months.
EN PRENSA. Paediatric and Perinatal Epidemiology.
- AUTHORS: Fernández-Somoano A, Álvarez-Avellón SM, Souto-García A, Vioque J, Navarrete-Muñoz EM, Tardón A.
TITLE: Alcohol Consumption and Lung Cancer According to Ile349Val Polymorphism in ADH3 Gene: Beyond the Tobacco Smoking Effect.
J Cancer. 2017 Jul 20; 8(12):2296-2302. doi: 10.7150/jca.18853. eCollection 2017. PubMed PMID: 28819433; PubMed Central PMCID: PMC5560148.
- AUTHORS: Álvarez-Avellón SM, Fernández-Somoano A, Navarrete-Muñoz EM, Vioque J, Tardón A.
TITLE: Effect of alcohol and its metabolites in lung cancer: CAPUA study.
Med Clin (Barc). 2017 Jun 21; 148(12):531-538. doi: 10.1016/j.medcli.2016.12.033. Epub 2017, Feb 22. English, Spanish. PubMed PMID: 28236470.
- AUTHORS: Tardon A.
TITLE: Genetic polymorphisms and lung cancer risk.
Med Clin (Barc). 2014 Aug 4; 143(3):113-4. doi: 10.1016/j.medcli.2013.12.004. Epub 2014 Jan 21. Spanish. PubMed PMID: 24456923.
- AUTHORS: Souto-García A, Fernández-Somoano A, Pascual T, Álvarez-Avellón SM, Tardón A.
TITLE: Association of p21 Ser31Arg and p53 Arg72Pro polymorphisms with lung cancer risk in CAPUA study.
Lung Cancer (Auckl). 2012 Nov 21; 3:69-78. doi: 10.2147/LCTT.S35287. eCollection 2012. PubMed PMID: 28210126; PubMed Central. PMCID: PMC5312605.
- AUTHORS: López-Cima MF, Alvarez-Avellón SM, Pascual T, Fernández-Somoano A, Tardón A.
TITLE: Genetic polymorphisms in CYP1A1, GSTM1, GSTP1 and GSTT1 metabolic genes and risk of lung cancer in Asturias.
BMC Cancer. 2012 Sep 27;12:433. doi: 10.1186/1471-2407-12-433. PubMed PMID: 23013535; PubMed Central PMCID: PMC3518149.
- AUTHORS: González-Arriaga P, Pascual T, García-Alvarez A, Fernández-Somoano A, López-Cima MF, Tardón A.
TITLE: Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival.
BMC Cancer. 2012 Mar 28; 12:121. doi: 10.1186/1471-2407-12-121. PubMed PMID: 22455335; PubMed Central PMCID: PMC3350430.
- AUTHORS: López-Cima MF, García-Pérez J, Pérez-Gómez B, Aragonés N, López-Abente G, Tardón A, Pollán M.
TITLE: Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study.
Int J Health Geogr. 2011 Jan 25; 10:10. doi: 10.1186/1476-072X-10-10. PubMed PMID: 21266041; PubMed Central. PMCID: PMC3040690.
- AUTHORS: Leader A, Fernández-Somoano A, López-Cima MF, González-Arriaga P, Pascual T, Marrón MG, Tardón A.
TITLE: Educational inequalities in quantity, duration and type of tobacco consumption among lung cancer patients in Asturias: epidemiological analyses.
Psicothema. 2010 Nov; 22(4):634-40. PubMed PMID: 21044490.
- AUTHORS: Tardon A, Lee WJ, Delgado-Rodriguez M, Dosemeci M, Albanes D, Hoover R, Blair A.
TITLE: Leisure-time physical activity and lung cancer: a meta-analysis. Cancer Causes Control.
2005 May; 16(4):389-97. Review. PubMed PMID: 15953981; PubMed Central PMCID: PMC1255936.
|Principal Investigator||Title||Funding Body||Participating Institutions||Duration|
|Adonina Tardón García||Environmental contamination through exposure to persistent toxic substances and effects upon children’s physical, visual and cognitive development||Health Research Fund. Instituto de Salud Carlos III||30-09-2013 to 31-06-2018|
|Principal Investigator||Title||Funding Body||Participating Institutions||Co-Investigators||Number of Researchers||Duration|
|PROJECT FIS-FEDER PI15/00069|
|Francisco Javier Llorca Díaz||Integration of genetic big data and clinical data: breast cancer survival in the MCC-Spain study.||Instituto de Salud Carlos III||Universidad de Cantabria. Project conducted in: IUOPA, Universidad de Oviedo, Asturias, Spain||Guillermo Fernández Tardón||6||01-01-2016 to 30-06-2019|
|Principal Investigator||Title||Funding Body||Participating Researchers||Reference No||Duration|
|PROJECT FIS-FEDER PI18/01313|
|Ana Fernández Somoano||Evolution of socioeconomic and environmental inequalities in the geographical distribution of mortality in the main cities of Asturias (1996-2015): MEDEA3||Health Research Fund. Instituto de Salud Carlos III||FISS-PI18/01313||01-09-2018 to 01-10-2021|
|AECC (Spanish Association Against Cancer) GRANTS FOR TRANSLATIONAL GROUPS 2018|
|Adonina Tardón García: PI for the Asturian node . Víctor Moreno Aguado PI Coordinator||Moving towards precision medicine in cancer prevention through genetic and metabolomic screening||“AECC Grants for Coordinated Translational Groups 2018” from the Fundación Científica AECC||AECC 2018||02-07-2018 to 30-09-2021|
|FIS-FEDER PI18/01237 PROJECT|
|Jesus Ibarluzea Maurolagoitia||INMA-Ado-Urban . Urban environment, psychosocial surroundings and mental development in childhood and preadolescence||Health Research Fund. Instituto de Salud Carlos III||Guillermo Fernández Tardón and Rafael Vicente Castro Delgado||FISS-PI18/01237||01-09-2018 to 01-10-2021|
|Principal Investigator||Title||Funding Body||Participating Institutions||Duration||Public Funding|
|REFERENCE. GROUP 53. CIBERESP|
|Adonina Tardón García||CIBERESP (Network Centre for Biomedical Research: Epidemiology and Public Health)||Ministerio de Sanidad y Consumo. Instituto de Salud Carlos III||01-01-2007 – Ongoing|
|PUBLIC GRANT FOR THE UNIVERSIDAD DE OVIEDO IN HEALTH AND THE ENVIRONMENT|
|Adonina Tardón García||Public grant for the Universidad de Oviedo in health and the environment.||Consejería de Sanidad. Gobierno del Principado de Asturias.||Preventive Medicine and Public Health Section. Universidad de Oviedo.||March 2017 to 31-12-2018||€40,000 / year|
|Partnership between the Ayuntamiento de Gijón (Gijón City Council) and the Universidad de Oviedo on the PROJECT TO SET UP THE INMA GIJÓN COHORT|
|Adonina Tardón García||Public grant for the Universidad de Oviedo to set up the GIJÓN INMA COHORT.||Ayuntamiento de Gijón||Preventive Medicine and Public Health Section. Universidad de Oviedo.||March 2017 to 31-12-2017||€57,000|
|PhD Student||Title||Date of Viva||Centre|
|María Del Mar Martínez Suárez||Infection of surgical wounds: rate of occurrence and assessment in seven hospitals in Asturias. (2007-2015).||06-07-2018||Department of Medicine. Universidad de Oviedo|
|Mirko Peter Neumann||Mutations of the TP53 gene in lung cancer patients with occupational exposure to silica and the application of the gene in certain intracellular molecular pathways.||04-07-2017|
|Carmen Natal Ramos||Effectiveness and efficiency of population-level breast cancer screening programmes.||27-06-2017|
|Ana María Blanco Badillo||The expression of MUC1: its predictive and prognostic value in lung adenocarcinomas.||18-12-2015|
|Ana Souto García||Polymorphism in cell-cycle regulatory genes and lung cancer risk.||23-06-2015|
|Ana Cristina Rodríguez Dehli||The prevalence of vitamin D deficiency and insufficiency and associated factors in gestation and early childhood in northern Spain.||20-07-2015||Universidad de Oviedo|
|Sara María Álvarez Avellón||Polymorphism in alcohol, acetaldehyde and folate metabolism genes and lung cancer risk.||13-11-2015||Universidad de Oviedo Outstanding PhD Award|
|Ana Fernández Somoano||Exposure to air pollution in the INMA-Asturias cohort of pregnant women.
|28-11-2013||Universidad de Oviedo Outstanding PhD Award|
|José Antonio Cernuda Martínez||The perceived training, theoretical knowledge and practical skills in accident and emergency medicine of primary healthcare professionals in Asturias.||03-06-2016||Department of Medicine. Universidad de Oviedo|
- A phase 3, open-label, randomised, multicentre, 12 months, efficacy and safety study of weekly MOD-4023 compared to daily genotropin® therapy in pre-pubertal children with growth hormone deficiency (EUDRACT NUMBER: 2016-003874-42 CODE: CP-4-006. SPONSOR: OPKO Biologics Ltd. PROTOCOL: V. 1.0 29 Nov 2016). PI Isolina Riaño Galán at Hospital Universitario Central de Asturias.
- Phase 4 Study: “Observational study until adult height of a cohort of subjects born small for gestational age (SGA) and treated with a growth hormone ” (Code SER-GH-2005-01) (sponsored by Merck Serono Spain).
- Phase 4 Study: “Prospective, single-cohort, multicentre observational long-term study in short children born small for gestational age (SGA) after treatment with Saizen® (Code EMR 200098-008 / SALTO) (sponsored by Merck Serono SA).
- “Effectiveness, safety and cost-effectiveness of flash glucose monitoring system (FreeStyle Libre®) for diabetes mellitus: update“, by Isolina Riaño (e-notes, 4/12/2018)
- Meeting of the Sociedad Española de Epidemiología (Spanish Epidemiology Society) (22/3/2019)