Research Divisions

Primary Healthcare

Group LeaderChronicityRespiratory Disorders in Primary Healthcare Family Medicine and the UniversityAgeing and FrailtyCommunication and HealthEvidence-Based Physical ExaminationsA Holistic Approach to Excess Weight in ChildhoodNOTABLE PUBLICATIONSPROJECTS

 

Dr Rubén Villa

 

Rubén Villa Estébanez

  • Bachelor of Medicine and Surgery (Universidad de Oviedo, 1986)
    Doctor of Medicine and Surgery (Universidad de Oviedo, 1992)
    Consultant in Family and Community Medicine (Hospital San Agustín de Asturias, 1997)
  • Associate Lecturer in the Department of Medicine (Universidad de Oviedo)
    Tutor on the Family and Community Medicine in Asturias module (since May 2000)
    Honorary Collaborator in the Faculty of Medicine and Health Sciences, Universidad de Oviedo (since September 2007)
  • Contact: ruben.villa@sespa.es

Principal Investigator: José María Fernández Rodríguez-Lacín

  • Oscar Veiras del Rio
  • Angel Comas Fuentes
  • Ernesto Martinez Estrada
  • Ruben Villa Estebanez
  • José Fuentes Vigil
  • Javier Perez Fernandez
  • Juan Enrique Cimas Hernando
  • Daniel Pedro Moro Quesada
  • Erika Izquierdo Sarcia
  • Natalia Izquierdo Garcia
  • José Antonio Fidalgo González

Lines of Research

  • A project to improve the care provided to chronic patients in primary healthcare centres in Asturias (PROMETEA)
    • Diabetes
    • Ischaemic heart disease and cardiovascular risk
    • Chronic pain
    • Prostate pathology

Principal Investigator: Juan Enrique Cimas Hernando

  • Javier Pérez Fernández
  • Cristina Alonso Porcel
  • Alejandro Arce
  • Susana Suárez Piñera
  • Cristina Canal Suárez
  • Sara Ramajo Iglesias

Lines of Research

  • Highly-prevalent chronic respiratory diseases (smoking, asthma, COPD, OSAS, pneumonia, TBC, etc.)
  • Pulmonary function tests in primary healthcare

Principal Investigator: José Manuel Iglesias Sanmartín

  • Ángel Comas Fuentes
  • Guillermo García Velasco
  • Pablo Belderraín Belderraín
  • Carmen María Muñoz Trujillo
  • Rubén Villa Estébanez
  • Begoña González González

Lines of Research

  • New teaching methods in Family Medicine
  • Teaching assessment in Family Medicine

Principal Investigator: Salvador Tranche Iparraguirre

  • Carmen Alonso Alonso
  • Covadonga Monte LLavona
  • Olga Quiñones Hidalgo
  • Carmen Martin
  • Amor Suarez García
  • Rosa García
  • Marta González García
  • Ángeles Montero Rodríguez
  • Lara Menéndez González
  • Alba Riesgo García
  • Clavel Arce García
  • Mar Pizarro López
  • Carmen Lago García
  • Inés Montero Montes
  • María Gordo Bravo
  • María José Díaz Couso
  • Raquel Pérez Caserío
  • Luis López Menéndez
  • Lucía Fernández García
  • Manuel A. Pérez López

Lines of Research

  • Frailty
    • Epidemiological study of frailty in Asturias
    • Validating the FRAX tool’s calibration for the Spanish population using the FRIDEX model.
    • Chronic Kidney Disease
  • Institutionalised patients
    • From independence to dependence : how can we delay the process?
    • Coordination of health and social services: consent protocols
  • Community initiatives in active ageing
  • Patient safety for the elderly.

Principal Investigator: Guillermo García Velasco

  • Ana Valle
  • Mónica García López
  • Ana López Alonso
  • Bibiana Pérez Deago

Lines of Research

  • Clinical relationships and efficacy
  • Communicative behaviours and their connection to patient compliance and satisfaction
  • The causes of difficult interactions in healthcare visits
  • Sharing decisions with the patient

Principal Investigator: Rubén Villa Estébanez

  • Guillermo García Velasco
  • Ernesto Martínez Estrada
  • Sara Yebra Delgado
  • Marta Martinez Iban
  • Erika Izquierdo García
  • Oscar Veiras del Rio
  • Jose Manuel Garzón Hernández

Lines of Research

  • Physical examinations based on symptoms and evidence
  • Evidence-based physical examination of patients with a prevalent health problem
  • Catalogue of manoeuvres, description of technique, overall value

Principal Investigators: Isabel Mora Gandarillas / Begoña Domínguez Aurrecoechea

  • María Fernández Francés
  • María Ángeles Ordoñez Alonso
  • Mercedes Sarmiento Martínez
  • Encarnación Díez Estrada
  • Teresa García Alonso
  • Julio Alonso Lorenzo

Hypothesis and Objectives

Our hypothesis is as follows: by understanding the current situation, designing and developing holistic solutions with the collaboration of all relevant sectors, and enhancing research, it is possible to improve dietary and exercise habits, thereby enabling us to provide short, medium and long-term solutions to the problem of excess weight in the target population.

  • Riesgo García A. Manejo clínico de las mujeres que consultan en urgencias por patología cardiovascular: ¿existen diferencias respecto a los hombres?. Emergencias 2012; 24: 325 – 331.
  • Eliecer Coto; Carmen Díaz Corte; Salvador Tranche; Juan Gómez; Julián R Reguero; Belen Alonso; Sara Iglesias; Helena Gil Peña; Xueqian Yin; Pablo Coto-Segura. Genetic Variation in the H19-IGF2 Cluster Might Confer Risk of Developing Impaired Renal Function.DNA Cell Biol. 2018;37 (7): 617 – 625.
  • Eliecer Coto; Carmen Diez-Corte; Salvador Tranche; Juan Gómez; Belén Alonso; S Iglesias; JR Reguero; C López-Larrea; P Coto-Segura. Gene variants in the NF-KB pathway (NFKB1, NFKBIA, NFKBIZ) and their association with type 2 diabetes and impaired renal function. Hum Immunol. 2018;79 (6): 494 – 498.
  • A Cases; I Egocheaga; S Tranche; V Pallares; R Ojeda; JL Gorriz; JM Portoles. Anemia of chronic kidney disease: Protocol of study, management and referral to Nephrology.Nefrologia. 2018;238 (1): 8 – 12.
  • Juan Gómez; Rebeca Lorca; Julián R. Reguero; Cesar Moris; Maria Martin; Salvador Tranche; Belén Alonso; Sara Iglesias; Beatriz Diaz Molina; Pablo Avanzas; Eliecer Coto. Screening of the Filamin C Gene in a Large Cohort of Hypertrophic Cardiomyopathy Patients.Circ Cardiovasc Genet. 2017;10 (2): e001584
  • Remedios Martin Alvarez; Salvador Tranche Iparraguirre. Sobrediagnóstico, cuando las personas reciben un diagnóstico que no necesitan. Atención Primaria 2016;48 (10): 619 – 620.
  • C Riobello; J Gómez; H Gil-Peña; S Tranche; JR Reguero; JM de la Hera; E Delgado; D Calvo; C Moris; F Santos; P Coto-Segura; S Iglesias; B Alonso. KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort. Mol Cell Endocrinol. 2016;427: 86 – 91.
  • Salvador Tranche Iparraguirre; Carlos Brotons; Beatriz Pascual de la Pisa; Ramón Macias; Eduardo Hevia Rodríguez; Merçe Marzo Castillo. Impact of a soy drink on climacteric symptoms: an open-label, crossover, randomized clinical trial. Gynelogical Endocrinology 2016;34: 1-6.
  • J Gómez; C Díaz Corte; Salvador Tranche; F Álvarez; S Iglesias; B Alonso; Eliecer Coto. Next generation sequencing search for uromodulin gene variants related with impaired renal function. Molecular Biology Report. 2015;42(9):1353 – 1358.
  • Eliecer Coto; Juan Gómez; Beatriz Suarez; Salvador Tranche Iparraguirre; Carmen Díaz Corte; Alberto Ortiz; Marta Ruiz-Ortega; Pablo Coto Segura; Ana Batalla; Carlos López Larrea. Association between the IL17RArs4819554 polymorphism and reduced renal filtration rate in the Spanish RENASTUR cohort. Human Immunology. 2015; 76: 75 – 78.
  • C LLor; L Bjerrum; A Munck; JM Cots; S Hernandez; A Moragas; S Hernandez; S Hernandez. Access to point-of-care tests reduces the prescription of antibiotics among antibiotic-requesting subjects with respiratory tract infections. Respir Care 2014;59 (12):1918 – 1923.
  • Mostaza JM; Lahoz C; Morales-Olivas F; Pinto X; Tranche S. Risk of pharmacological interactions due to the co-administration of statins and cytochrome P450 isoenzyme 3A4-metabolized drugs: Multicenter, crossover study. Med Clin (Barc) 2014;143 (10):427 – 432.
  • Marta Sánchez-Celaya del Pozo; Salvador Tranche Iparraguirre. Documento de consenso sobre la enfermedad renal crónica: Una oportunidad para la coordinación. Atención Primaria. 2014;46 (9):453 – 454.
  • JM Cots; S Hernandez; J Ortega; J Arranz; C Llor. Effectiveness of two types of intervention on antibiotic prescribing in respiratory tract infections in Primary Care in Spain. Happy Audit Study. Atención Primaria 2014;46 (9): 492 – 500.
  • Eliecer Coto; Beatriz Tavira; Juan Gómez; Salvador Tranche Iparraguirre. Effect of the FTO rs990506 polymorphism on the main comorbidities of the Cardiorenal Metabolic Syndrome in an carioelderly Spanish cohort. Cardiorenal Med 2014;4: 82 – 87.
  • Josep Basora Gallisa; Domingo Orozco Beltrán; Salvador Tranche Iparraguirre. Atención Primaria hacia el open access. Atención Primaria 2013;45 (2):69 – 70.
  • Ortega F; Tavira B; Gomez J; Tranche S. A CLCNKA polymorphism (rs10927887; p.Arg83Gly) previously linked to heart failure is associated with the estimated glomerular filtration rate in the RENASTUR cohort. Gene 2013;527 (2): 670 – 672.
  • Tavira B; Gomez J; Coto E; Tranche S. A Common APOE Polymorphism Is an Independent Risk Factor for Reduced Glomerular Filtration Rate in the Spanish RENASTUR Cohort. Cardiorenal Med 2013;3 (2): 113 – 119.
  • Francisco Camarales; Salvador Tranche; JM Gómez. Semana del Autocuidado semFYC. Atención Primaria 2013;45: 229 – 20.
  • Alberto Martínez Castelao; José L. Gorriz; Jordi Bover; Julián Segura de la Morena; Jesús Cebollada; Javier Escalada; Enric esmatjes; Lorenzo Fácila; Javier Gamarra; Silvia Grácia; Julio Hernández Moreno; Jose L. LListerri cano; Pilar Mazón; Rosario Montañes; Francisco Morales Olivas; Manuel Muñoz Torres; Pedo de Pablos Velasco; Carmen Suarez; Salvador Tranche Iparraguirre. Documento de Consenso para la detección y manejo de la Enfermedad Renal Crónica. Nefrología 2014;4:243- 262

A study of renal and cardiovascular health in Asturias: the Renasturias Study

  • Principal investigator: Salvador Tranche
  • Oficina de Investigación Biosanitaria (Biomedical Research Office) – FICYT (Foundation for the Promotion of Applied Scientific Research and Technology in Asturias)